In this work, a novel formulation of polysulfobetaine, poly (sulfobetaine-acrylamide-allyl glycidyl ether) (PSPB-AM-AGE), was synthesized and grafted onto cotton. The synthesis of PSPB-AM-AGE and its grafting on the cotton fabrics were confirmed by FTIR, XPS and SEM. The PSPB-AM-AGE treated cotton fabrics exhibited a high level of antibacterial rate against both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), which are 95.18% and 98.74%, separately, as well as a good laundry durability. The mechanical tests showed that the essential cotton properties can be largely preserved in the treatment process. Moreover, the hydrophilicity, air and water permeability of the cotton were improved after treated with PSPB-AM-AGE, indicating a better wearing comfort performance. The whiteness of the cotton fabrics did not decrease significantly. The safety evaluation demonstrated that PSPB-AM-AGE had no cytotoxicity. The developed antibacterial finishing introduced a new method to apply polysulfobetaine interfaced on cellulose, providing great potential for biomedical fabric application.

在这项工作中，合成了一种新的聚磺基甜菜碱配方聚（磺基甜菜碱-丙烯酰胺-烯丙基缩水甘油醚）（PSPB-AM-AGE）并接枝到棉花上。FTIR、XPS和SEM证实了PSPB-AM-AGE的合成及其在棉织物上的接枝。PSPB-AM-AGE 处理的棉织物对大肠杆菌（E. coli）和金黄色葡萄球菌（S. aureus）均表现出高水平的抗菌率，分别为 95.18% 和 98.74%，以及良好的耐洗性。机械测试表明，棉花的基本特性可以在处理过程中得到很大程度的保留。此外，经PSPB-AM-AGE处理后，棉的亲水性、透气性和透水性均有所提高，具有更好的穿着舒适性。棉织物的白度没有明显下降。安全性评估表明 PSPB-AM-AGE 没有细胞毒性。开发的抗菌整理引入了一种在纤维素上应用聚磺基甜菜碱的新方法，为生物医用织物的应用提供了巨大的潜力。