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Molecular and biological functions of resveratrol in psychiatric disorders: a review of recent evidence
Cell and Bioscience ( IF 7.5 ) Pub Date : 2020-11-07 , DOI: 10.1186/s13578-020-00491-3
Mehran Shayganfard

Mental disorders including depression, anxiety, schizophrenia, autism spectrum disorders, bipolar and etc. have a considerable proportion of global disorder burden. Many nutritional psychiatry investigations have been conducted to evaluate the relationship between several individual nutrients such as herbal compounds with mental health. Resveratrol, a famous polyphenol compound, is known as an antioxidant, anti-inflammatory, anti-apoptotic, and neuroprotective agent regulating the function of brain and improves the behavioral factors associated with learning, anxiety, depression, and memory. In addition, this natural compound can cross the blood–brain barrier representing neurological influences. The pharmacological interest of utilizing resveratrol in mental disorders is due to its anti-inflammatory and antioxidant features. The aim of this paper was to review the studies evaluated the potential effects of resveratrol on mental disorders.

中文翻译:

白藜芦醇在精神疾病中的分子和生物学功能:近期证据综述

精神障碍,包括抑郁症,焦虑症,精神分裂症,自闭症谱系障碍,躁郁症等,在全球疾病负担中占相当大的比例。已经进行了许多营养精神病学研究,以评估几种单独营养素(例如草药化合物)与心理健康之间的关系。白藜芦醇是一种著名的多酚化合物,被称为抗氧化剂,消炎药,抗凋亡药和神经保护剂,可调节大脑功能并改善与学习,焦虑,抑郁和记忆有关的行为因素。此外,这种天然化合物可以穿过血脑屏障,代表神经系统的影响。在精神障碍中使用白藜芦醇的药理学兴趣归因于其抗炎和抗氧化功能。
更新日期:2020-11-09
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