Recent Advances in Transition Metal Free Synthetic Protocols for Quinoline Derivatives,Current Organic Chemistry

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Recent Advances in Transition Metal Free Synthetic Protocols for Quinoline Derivatives
Current Organic Chemistry ( IF 1.7 ) Pub Date : 2020-07-31 , DOI: 10.2174/1385272824999200616122557
Rukhsana Tabassum ₁ , Muhammad Ashfaq ₁ , Hiroyuki Oku ₂

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The quinoline moiety is a privileged scaffold among heterocyclic compounds that is an important construction motif in the fields of pharmaceutical chemistry. Quinoline molecule possesses a variety of therapeutic activities like antiviral, antimalarial, antibacterial, antitumor, anticancer, antioxidant antihypertensive, antifungal, anthelmintic, cardiotonic, anticonvulsant and anti-inflammatory. This review provides an insight into recent development in transition metal free novel and modified conventional synthetic routes to yield a wide variety of substituted quinolines.

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