The default-mode network (DMN) is believed to be associated with levels of consciousness, but how the functional connectivity (FC) of the DMN changes across different states of consciousness is still unclear. In the current work, we addressed this issue by exploring the coactive micropattern (CAMP) networks of the DMN according to the CAMPs of rat DMN activity during the sleep-wake cycle and tracking their topological alterations among different states of consciousness. Three CAMP networks were observed in DMN activity, and they displayed greater FC and higher efficiency than the original DMN structure in all states of consciousness, implying more efficient information processing in the CAMP networks. Furthermore, no significant differences in FC or network properties were found among the three CAMP networks in the waking state. However, the three networks were distinct in their characteristics in two sleep states, indicating that different CAMP networks played specific roles in distinct sleep states. In addition, we found that the changes in the FC and network properties of the CAMP networks were similar to those in the original DMN structure, suggesting intrinsic effects of various states of consciousness on DMN dynamics. Our findings revealed three underlying CAMP networks within the DMN dynamics and deepened the current knowledge concerning FC alterations in the DMN during conscious changes in the sleep-wake cycle.

中文翻译：

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睡眠-唤醒周期中默认模式网络中的更改的主动微模式连接性

默认模式网络（DMN）被认为与意识水平相关，但是DMN的功能连接性（FC）在不同意识状态之间如何变化仍然不清楚。在当前的工作中，我们通过在睡眠-觉醒周期中根据大鼠DMN活动的CAMP探索DMN的协同微模式（CAMP）网络，并跟踪它们在不同意识状态之间的拓扑变化，来解决此问题。在DMN活动中观察到三个CAMP网络，它们在所有意识状态下均显示出比原始DMN结构更高的FC和更高的效率，这意味着CAMP网络中的信息处理效率更高。此外，在处于唤醒状态的三个CAMP网络之间，FC或网络属性没有发现显着差异。然而，这三个网络在两个睡眠状态下的特征是不同的，这表明不同的CAMP网络在不同的睡眠状态下起特定的作用。此外，我们发现CAMP网络的FC和网络属性的变化与原始DMN结构中的变化相似，表明各种意识状态对DMN动力学的内在影响。我们的发现揭示了DMN动力学中的三个基本CAMP网络，并加深了有关在觉醒觉醒周期中DMN中FC改变的当前知识。我们发现，CAMP网络的FC和网络属性的变化与原始DMN结构中的变化相似，表明各种意识状态对DMN动力学的内在影响。我们的发现揭示了DMN动力学中的三个基本CAMP网络，并加深了有关在觉醒觉醒周期中DMN中FC改变的当前知识。我们发现，CAMP网络的FC和网络属性的变化与原始DMN结构中的变化相似，表明各种意识状态对DMN动力学的内在影响。我们的发现揭示了DMN动力学中的三个基本CAMP网络，并加深了有关在觉醒觉醒周期中DMN中FC改变的当前知识。