Sugar transporter (SUT) genes are associated with multiple physiological and biochemical processes in filamentous fungi, such as the response to various stresses. However, limited systematic analysis and functional information of SUT gene family have been available on Aspergillus oryzae (A. oryzae). To investigate the potential roles of SUTs in A. oryzae, we performed an integrative analysis of the SUT gene family in this study. Based on the conserved protein domain search, 127 putative SUT genes were identified in A. oryzae and further categorized into eight distinct subfamilies. The result of gene structure and conserved motif analysis illustrated functional similarities among the AoSUT proteins within the same subfamily. Additionally, expression profiles of the AoSUT genes at different growth stages elucidated that most of AoSUT genes have high expression levels at the stationary phase while low in the adaptive phase. Furthermore, expression profiles of AoSUT genes under salt stress showed that AoSUT genes may be closely linked to salt tolerance and involved in sophisticated transcriptional process. The protein-protein interaction network of AoSUT propounded some potentially interacting proteins. A comprehensive overview of the AoSUT gene family will offer new insights into the structural and functional features as well as facilitate further research on the roles of AoSUT genes in response to abiotic stresses.

中文翻译：

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米曲霉糖转运蛋白基因家族的鉴定及表达分析


糖转运蛋白（SUT）基因与丝状真菌中的多种生理生化过程相关，例如对各种胁迫的反应。然而，对米曲霉（ A. oryzae ）的SUT基因家族的系统分析和功能信息有限。为了研究 SUT 在米曲霉中的潜在作用，我们在本研究中对 SUT 基因家族进行了综合分析。基于保守蛋白结构域搜索，在米曲霉中鉴定出了 127 个假定的 SUT 基因，并进一步分为 8 个不同的亚科。基因结构和保守基序分析的结果说明了同一亚家族内的 AoSUT 蛋白之间的功能相似性。此外，AoSUT基因在不同生长阶段的表达谱表明，大多数AoSUT基因在稳定期表达水平较高，而在适应期表达水平较低。此外，盐胁迫下 AoSUT 基因的表达谱表明，AoSUT 基因可能与耐盐性密切相关，并参与复杂的转录过程。 AoSUT 的蛋白质-蛋白质相互作用网络提出了一些潜在的相互作用蛋白质。对 AoSUT 基因家族的全面概述将为结构和功能特征提供新的见解，并有助于进一步研究 AoSUT 基因在响应非生物胁迫中的作用。