ABSTRACT

Introduction

COVID-19 pandemic has been declared as a global emergency by the World Health Organization which has mounted global pressure on the healthcare system. The design and development of rapid tests for the precise and early detection of infection are urgently needed to detect the disease and also for bulk screening of infected persons. The traditional drugs moderately control the symptoms, but so far, no specific drug has been discovered. The prime concern is to device novel tools for rapid and precise diagnosis, drug delivery, and effective therapies for coronavirus. In this context, nanotechnology offers novel ways to fight against COVID-19.

Area covered

This review includes the use of nanomaterials for the control of COVID-19. The tools for diagnosis of coronavirus, nano-based vaccines, and nanoparticles as a drug delivery system for the treatment of virus infection have been discussed. The toxicity issues related to nanoparticles have also been addressed.

Expert opinion

The research on nanotechnology-based diagnosis, drug delivery, and antiviral therapies is at a preliminary stage. The antiviral nanomedicine therapies are cost-effective and with high quality. Nanoparticles are a promising tool for prevention, diagnosis, antiviral drug delivery, and therapeutics, which may open up new avenues in the treatment of COVID-19.

中文翻译：

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基于纳米技术的 COVID-19 管理有前景的策略：当前的发展和限制

摘要

介绍

世界卫生组织已宣布 COVID-19 大流行为全球紧急情况，这对医疗保健系统造成了全球压力。迫切需要设计和开发用于精确和早期检测感染的快速检测方法，以检测疾病以及对感染者进行大规模筛查。传统药物对症状有一定的控制作用，但目前还没有发现特效药。主要关注的是为冠状病毒的快速和精确诊断、药物输送和有效治疗提供新的工具。在这种情况下，纳米技术提供了对抗 COVID-19 的新方法。

覆盖面积

本综述包括使用纳米材料控制 COVID-19。已经讨论了用于诊断冠状病毒的工具、纳米疫苗和纳米粒子作为治疗病毒感染的药物递送系统。与纳米粒子有关的毒性问题也已得到解决。

专家意见

基于纳米技术的诊断、药物输送和抗病毒治疗的研究处于初步阶段。抗病毒纳米药物疗法具有成本效益和高质量。纳米颗粒是一种很有前途的预防、诊断、抗病毒药物递送和治疗工具，可能为治疗 COVID-19 开辟新途径。