Research question

: Is there a relationship between endometriosis and placenta previa (PP)?

Design

To investigate if there is a relationship between endometriosis and PP a retrospective study was carried out, using prospectively recorded data from two different data-bases from Cruces University Hospital. Two different populations were included in the study. The ART (assisted reproduction techniques) population consisted of 246 cesarean sections (CS), from a total of 1170 deliveries, all of them resulting from ART and the Obstetrics population consisted of 7045 CS, from a total of 50298 deliveries. A representative subset was established selecting 4 CS without endometriosis for each CS with endometriosis.

Results

In our ART population, the PP rate was 1.71% among all deliveries and 8.13% among CS. In our general obstetric population, the PP rate was 0.34% among all deliveries and 2.41% among the CS. Among the CS in ART pregnancies, the PP rate was 20% in the women with endometriosis vs 5.47% in the other women (OR= 4.32; 95% CI =1.67- 11.17), while considering all ART deliveries, the PP rates were 6.43% and 1.07% respectively (OR= 6.36; 95% CI= 2.59-15.65). In the CS-Obstetrics population, the rate of PP was 12.05% among women with endometriosis vs 2.73% among women without endometriosis (OR = 4.89; 95% CI=2. 52- 9. 47). Considering all deliveries, the PP rate was 1.35% among women with endometriosis vs 0.2% in other women.

Differences persisted when adjusting for age, IVF, multiplicity and previous deliveries.

Conclusion(s)

Endometriosis is associated with a higher risk of PP even after adjusting for other parameters.

中文翻译：

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子宫内膜异位是前置胎盘的危险因素：来自同一家医院的两种不同剖宫产记录之间的一致性。

研究问题

：子宫内膜异位与前置胎盘（PP）有关系吗？

设计

为了调查是否存在使用来自两个不同的数据基础前瞻性记录数据子宫内膜异位和PP的回顾性研究之间的关系进行了，Ç ruces大学医院。该研究包括两个不同的人群。ART（辅助生殖技术）人群包括246例剖宫产（CS），共分娩1170例，所有这些都是ART和妇产科人群的7045 CS（共50298例）。建立代表性子集，为每个患有子宫内膜异位的CS选择4个没有子宫内膜异位的CS。

结果

在我们的ART人群中，所有分娩的PP发生率分别为1.71％和CS的8.13％。在我们的普通产科人群中，所有分娩中的PP发生率分别为0.34％和CS中的2.41％。在接受ART妊娠的CS中，子宫内膜异位症妇女的PP率为20％，其他妇女为5.47％（OR = 4.32； 95％CI = 1.67-11.17），而考虑所有ART分娩，PP率为6.43 ％和1.07％（OR ＝ 6.36； 95％CI ＝ 2.59-15.65）。在CS产科人群中，子宫内膜异位症妇女的PP发生率为12.05％，而子宫内膜异位症妇女的PP发生率为2.73％（OR = 4.89； 95％CI = 2。52-9。47）。考虑到所有分娩，子宫内膜异位症妇女的PP率为1.35％，而其他妇女为0.2％。

在调整年龄，IVF，多重性和以前分娩时，差异仍然存在。

结论

即使调整其他参数，子宫内膜异位症也有较高的PP风险。