Objective

In the present study, we aimed at examining the volumes of the insula in more pure patients with a social anxiety disorder.

Methods

We examined twenty-one patients with social anxiety disorder according to DSM-IV and twenty healthy controls. All patients and controls were applied to magnetic resonance imaging (MRI). Insula volumes were measured by using the manual tracing method in accordance with the standard anatomical atlases and related previous studies on insula volumes.

Results

We found that the mean posterior and anterior insula volumes for both sides of patients were statistically significantly reduced compared to those of healthy control subjects.

Conclusion

Consequently, in the present study, we found that patients with a social anxiety disorder had reduced insula volumes compared to those of healthy control subjects. However, to get strong this finding, novel studies with a larger sample size are required.

中文翻译：

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社交焦虑症患者的脑岛体积发生改变

客观的

在本研究中，我们旨在检查更纯粹的社交焦虑症患者的脑岛体积。

方法

我们根据 DSM-IV 检查了 21 名患有社交焦虑症的患者和 20 名健康对照者。所有患者和对照组均进行磁共振成像 (MRI)。根据标准解剖图谱和之前有关脑岛体积的相关研究，使用手动追踪方法测量脑岛体积。

结果

我们发现，与健康对照组相比，患者两侧的平均后脑岛体积和前脑岛体积在统计学上显着降低。

结论

因此，在本研究中，我们发现与健康对照受试者相比，患有社交焦虑症的患者的脑岛体积减少。然而，为了获得强有力的这一发现，需要更大样本量的新研究。