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A rare case of Clostridium paraputrificum bacteremia in a 78-year-old Caucasian man diagnosed with an intestinal neoplasm
Anaerobe ( IF 2.5 ) Pub Date : 2020-11-07 , DOI: 10.1016/j.anaerobe.2020.102292
J Intra 1 , A Milano 1 , C Sarto 1 , P Brambilla 1
Affiliation  

Clostridium like species, particularly Clostridium perfrigens, are the second most common causes of human anaerobic infections, including myonecrosis and bacteremia. Clostridium paraputrificum is an infrequent isolate, which has been identified in only 1% of reported cases of clostridial infections. We herein report a rare case of C. paraputrificum bacteremia in a 78-year-old Caucasian man diagnosed with an intestinal carcinoma and liver neoplastic lesions. The isolate was susceptible to chloramphenicol, meropenem, metronidazole, vancomycin, and resistant to clindamycin and penicillin, and the patient was successfully treated with metronidazole. Malignancy and inflammatory bowel diseases are often associated with clostridial bacteremia, which cannot be neglected.



中文翻译:

一例 78 岁白人男性被诊断患有肠道肿瘤的副腐烂梭菌菌血症罕见病例

梭菌样物种,尤其是产气梭菌,是人类厌氧菌感染(包括肌坏死和菌血症)的第二大常见原因。Clostridium paraputrificum是一种罕见的分离株,仅在 1% 的梭菌感染报告病例中被发现。我们在此报告了一个罕见的C. paraputrificum 病例一名 78 岁的白人男性被诊断患有肠癌和肝脏肿瘤病变的菌血症。分离株对氯霉素、美罗培南、甲硝唑、万古霉素敏感,对克林霉素和青霉素耐药,患者用甲硝唑治疗成功。恶性肿瘤和炎症性肠病常与梭菌菌血症有关,不容忽视。

更新日期:2020-11-18
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