Flavonoids are members of polyphenolic compounds, which are naturally presented in fruits, vegetables, and some medicinal plants. Traditionally, the root of Scutellaria baicalensis is widely used as Chinese herbal medicine and contains several major bioactive compounds such as Wogonin, Scutellarein, Baicalein, and Baicalin. Experimental and clinical evidence has been proving that Wogonin exhibits diverse biological activities such as anti-cancer, anti-inflammation, and treatment of bacterial and viral infections. In this review, we summarize and emphasize the benefits of Wogonin as a therapeutic adjuvant for anti-viral infection, anti-inflammation, neuroprotection as well as anxiolytic and anticonvulsant. Moreover, the molecular mechanism(s) how Wogonin mediates the cellular signal pathways and immune responses are also discussed and highlighted valuable properties of Wogonin in multiple therapies.

类黄酮是多酚化合物的成员，多酚化合物天然存在于水果，蔬菜和某些药用植物中。传统上，黄cut的根被广泛用作中草药，并且包含几种主要的生物活性化合物，例如Wogonin，Scutellarein，Baicalein和Baicalin。实验和临床证据已证明，Wogonin具有多种生物活性，例如抗癌，抗炎以及细菌和病毒感染的治疗。在这篇综述中，我们总结并强调了Wogonin作为抗病毒感染，抗炎，神经保护以及抗焦虑药和抗惊厥药的治疗佐剂的优势。此外，还讨论了Wogonin如何介导细胞信号途径和免疫应答的分子机制，并突出了Wogonin在多种疗法中的有价值的特性。