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Antimicrobial and anti-inflammatory activities of australian native plants in the context of wound healing: A review
Biologia ( IF 1.4 ) Pub Date : 2020-11-09 , DOI: 10.2478/s11756-020-00636-2
Manirujjaman Manirujjaman , Trudi Collet

Wound healing is an essential biological process which involves tissue repair and recovery and includes the action of a complex system of blood cells, cytokines, and growth factors. It is a process attended by integrated cellular and biochemical events and characterized by four phases: haemostasis, inflammation, proliferation, and remodelling. Medicinal plants which have healing applications, continue to play a central role in the healthcare system of a large proportion of the world’s population. Numerous studies have shown that several Australian plant species used medicinally, contain biologically active extracts and compounds which have enormous potential for the treatment and management of a wound. Medicinal plants contain a wide range of chemical compounds as the unique flora of Australia offers an array of diverse bioactives, which elicit antibacterial, antioxidant, anti-inflammatory and wound healing abilities. Such properties are not limited to the edible sections of plants as the roots, bark, sap, leaves and seeds from a vast array of plants have demonstrated similar effects. In this review article, various Australian native plants which are scientifically proven to have antibacterial and anti-inflammatory properties that support wound healing, are discussed. This review also briefly discusses the general wound healing process, wound-colonizing bacteria, factors that affect wound healing, and costs involved in the treatment and management of chronic wounds.



中文翻译:

伤口愈合过程中澳大利亚本土植物的抗菌和抗炎活性:综述

伤口愈合是必不可少的生物学过程,涉及组织修复和恢复,包括血细胞,细胞因子和生长因子等复杂系统的作用。这是一个由细胞和生化综合事件参与的过程,其特征在于四个阶段:止血,炎症,增殖和重塑。具有治疗作用的药用植物继续在世界上很大一部分人口的医疗保健系统中发挥核心作用。大量研究表明,药用的几种澳大利亚植物都含有具有生物活性的提取物和化合物,这些化合物在治疗和控制伤口方面具有巨大的潜力。药用植物包含多种化学物质,因为澳大利亚独特的植物区系提供了多种多样的生物活性物质,具有抗菌,抗氧化,消炎和伤口愈合的能力。这样的性质不限于植物的可食用部分,因为来自大量植物的根,树皮,树汁,叶子和种子已显示出相似的作用。在这篇综述文章中,讨论了各种澳大利亚本土植物,这些植物经过科学证明具有支持伤口愈合的抗菌和抗炎特性。本文还简要讨论了一般的伤口愈合过程,伤口定殖细菌,影响伤口愈合的因素以及慢性伤口的治疗和管理费用。大量植物的叶子和种子也表现出类似的效果。在这篇综述文章中,讨论了各种澳大利亚本土植物,这些植物经过科学证明具有支持伤口愈合的抗菌和抗炎特性。本文还简要讨论了一般的伤口愈合过程,伤口定殖细菌,影响伤口愈合的因素以及慢性伤口的治疗和管理费用。大量植物的叶子和种子也表现出类似的效果。在这篇综述文章中,讨论了各种澳大利亚本土植物,这些植物经过科学证明具有支持伤口愈合的抗菌和抗炎特性。这篇综述还简要讨论了一般的伤口愈合过程,伤口定殖细菌,影响伤口愈合的因素以及涉及慢性伤口的治疗和管理的成本。

更新日期:2020-11-09
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