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Epitope masking may limit antibody boosting to malaria vaccines
Immunology and Cell Biology ( IF 3.2 ) Pub Date : 2020-11-05 , DOI: 10.1111/imcb.12415 Liriye Kurtovic 1, 2 , Michelle J Boyle 1, 3 , James G Beeson 1, 2, 4, 5
Immunology and Cell Biology ( IF 3.2 ) Pub Date : 2020-11-05 , DOI: 10.1111/imcb.12415 Liriye Kurtovic 1, 2 , Michelle J Boyle 1, 3 , James G Beeson 1, 2, 4, 5
Affiliation
We discuss the study by McNamara et al., who report that low levels of antigen‐specific antibodies in serum can limit the boosting of antibody and B‐cell responses following immunization with live attenuated malaria sporozoites.
中文翻译:
表位掩蔽可能会限制对疟疾疫苗的抗体增强
我们讨论了 McNamara等人的研究,他们报告说血清中低水平的抗原特异性抗体会限制减毒活疟疾子孢子免疫后抗体和 B 细胞反应的增强。
更新日期:2020-11-05
中文翻译:
表位掩蔽可能会限制对疟疾疫苗的抗体增强
我们讨论了 McNamara等人的研究,他们报告说血清中低水平的抗原特异性抗体会限制减毒活疟疾子孢子免疫后抗体和 B 细胞反应的增强。