Efforts to eliminate schistosomiasis are hindered by incomplete efficacy of the only FDA-approved antischistosomal drug, praziquantel. By using postgenomic technologies, Wendt et al. and Wang et al. deciphered the function of several genes required for worm survival and pathogenesis, which opens the way for the development of innovative parasite-targeted therapies.

中文翻译：

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血吸虫中的高热组学

FDA批准的唯一抗血吸虫病药物吡喹酮的疗效不完全，阻碍了消除血吸虫病的努力。通过使用后基因组技术，Wendt等人。和Wang等。破译了蠕虫生存和发病机理所需的几种基因的功能，这为开发创新的针对寄生虫的疗法开辟了道路。