The rational design and fabrication of ordered mesoporous materials with highly exposed surface area are of great significance to address the fundamental challenges in electrochemistry-related applications by providing more active sites and fast ion/gas diffusion channel. In this work, a self-template method is reported to prepare hollow-structured mesoporous carbon (HOMC) nanoplates by depositing resol-F127 micelles onto the surface of metal-organic-framework (MOF) nanoplates, followed by hydrothermal reaction and carbonization. The parameters influencing the morphology and microstructure of the HOMC materials, i.e., the MOF-to-resol-F127 ratio and the concentration of resol-F127 micelles, are systematically investigated. Fe-doped HOMC (Fe/HOMC-1000) is obtained after carbonization, as a result from adding FeCl₃ during the hydrothermal reaction. Benefiting from morphological aspects, such as the nanoplate shape, the hollow structure, and mesoporous walls, the Fe/HOMC-1000 exhibits higher electrocatalytic activity and efficiency than the commercial Pt/C during oxygen reduction reaction (ORR). In addition, the better durability and higher tolerance to methanol of Fe/HOMC-1000 than Pt/C indicate the advantages of Fe/HOMC-1000 in the ORR application. The assembled Zn-air battery demonstrates high power densities with excellent cycling stability. The strategy proposed here can provide a new avenue for the design of ordered mesoporous materials with hollow structure for a wide variety of applications.