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Shortening of NMR 1/ T 1 and 1/ T 2 Relaxation Rate Distribution Intervals in D 2 O Containing Jaw Cysts or Abscesses: Separation of Cysts from Abscesses
Journal of Applied Spectroscopy ( IF 0.8 ) Pub Date : 2020-11-06 , DOI: 10.1007/s10812-020-01093-0
U. N. Yilmaz , B. D. Yilmaz

It is well known that the relaxation rates (1/T1 and 1/T2) in H2O/D2O mixtures are smaller than those in H2O alone. The results of this have not been examined in the presence of a low rate of cysts or abscess contents in D2O. One purpose of this study was to determine the shortening of the relaxation rate distribution interval (SRDI) for D2O containing cysts or abscess contents. Another goal is to investigate the differentiation of cysts from abscesses with T1 and T2 measurements. The ultimate objective is the possibility of a new MRI contrast mechanism for dental lesions. Nineteen odontogenic jaw cysts and 12 jaw abscesses were collected from patients. A mixture was prepared by adding 0.06 mL cyst or abscess content to 0.94 mL D2O. The experiments were carried out with a nuclear magnetic resonance spectrometer operating at 400 MHz. The mean 1/T2 of the abscesses was significantly different from that of the cysts (P < 0.005), but the mean 1/T1 of the non-haemorrhagic cysts was not different from that of the abscesses (P = 0.626). The interval shortening ratios (SRDIs) of 1/T1 and 1/T2 for the cystic mixture were 16.36 and 4.22, respectively. The ratios were 8.39 and 2.68, respectively, for the mixture containing abscess contents. In conclusion, the relaxation rate reduction of the mixture results in a shortening of the distribution intervals, which leads to the separation of cysts from abscesses. In addition, the high interval shortening ratios indicate that the results of this study can provide a basis for studies on a new MR contrast mechanism for jaw lesions.



中文翻译:

含D 2 O的颚状囊肿或脓肿中NMR 1 / T 1和1 / T 2弛豫速率分布间隔的缩短:囊肿与脓肿的分离

众所周知,H 2 O / D 2 O混合物中的弛豫速率(1 / T 1和1 / T 2)小于单独的H 2 O中的弛豫速率。在D 2 O中存在低比率的囊肿或脓肿的情况下,尚未检查此结果。这项研究的目的之一是确定缩短D 2 O囊肿的弛豫率分布间隔(SRDI)或脓肿内容。另一个目标是研究T 1T 2脓肿与囊肿的分化测量。最终目标是为牙齿病变建立新的MRI对比机制的可能性。从患者中收集了19个牙源性颌囊肿和12个脓肿。通过向0.94 mL D 2 O中添加0.06 mL囊肿或脓肿来制备混合物。使用在400 MHz下运行的核磁共振波谱仪进行实验。脓肿的平均1 / T 2与囊肿的平均值有显着差异(P <0.005),但非出血性囊肿的平均1 / T 1与脓肿的平均值没有差异(P = 0.626)。1 / T 1和1 / T 2的间隔缩短率(SRDI)囊性混合物的分别为16.36和4.22。含有脓肿内容物的混合物的比率分别为8.39和2.68。总之,混合物松弛率的降低导致分布间隔的缩短,从而导致囊肿与脓肿分离。此外,较高的间隔缩短率表明该研究结果可为研究新的颌骨病变MR对比机制提供基础。

更新日期:2020-11-06
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