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COMPLEXITY-BASED CLASSIFICATION OF THE CORONAVIRUS GENOME VERSUS GENOMES OF THE HUMAN IMMUNODEFICIENCY VIRUS (HIV) AND DENGUE VIRUS
Fractals ( IF 3.3 ) Pub Date : 2020-07-13 , DOI: 10.1142/s0218348x20501297
HAMIDREZA NAMAZI 1
Affiliation  

Coronavirus disease (COVID-19) is a pandemic disease that has affected almost all around the world. The most crucial step in the treatment of patients with COVID-19 is to investigate about the coronavirus itself. In this research, for the first time, we analyze the complex structure of the coronavirus genome and compare it with the other two dangerous viruses, namely, dengue and HIV. For this purpose, we employ fractal theory, sample entropy, and approximate entropy to analyze the genome walk of coronavirus, dengue virus, and HIV. Based on the obtained results, the genome walk of coronavirus has greater complexity than the other two deadly viruses. The result of statistical analysis also showed the significant difference between the complexity of genome walks in case of all complexity measures. The result of this analysis opens new doors to scientists to consider the complexity of a virus genome as an index to investigate its danger for human life.

中文翻译:

基于复杂性的冠状病毒基因组与人类免疫缺陷病毒 (HIV) 和登革热病毒基因组的分类

冠状病毒病 (COVID-19) 是一种流行病,几乎影响了世界各地。治疗 COVID-19 患者的最关键步骤是调查冠状病毒本身。在这项研究中,我们首次分析了冠状病毒基因组的复杂结构,并将其与其他两种危险病毒,即登革热病毒和 HIV 病毒进行了比较。为此,我们采用分形理论、样本熵和近似熵来分析冠状病毒、登革热病毒和 HIV 的基因组行走。根据获得的结果,冠状病毒的基因组行走比其他两种致命病毒具有更大的复杂性。统计分析的结果还显示,在所有复杂度测量的情况下,基因组游走的复杂度之间存在显着差异。
更新日期:2020-07-13
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