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Global REACH 2018: Regional differences in cerebral blood velocity control during normoxic and hypoxic cold pressor tests
Autonomic Neuroscience ( IF 3.2 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.autneu.2020.102740
Michael M Tymko 1 , Ryan L Hoiland 2 , Philip N Ainslie 3
Affiliation  

The impact of oxygen on the cerebral response to the cold pressor test (CPT) remains unknown. In 13 participants, blood pressure, middle and posterior cerebral artery blood velocity (MCAv and PCAv, respectively) were measured during an isocapnic normoxic and hypoxic (SpO2 = 85%) CPT. The main findings were: 1) the MCAv response to the CPT was greater compared to the PCAv in both normoxic and hypoxic conditions (P = 0.003 and P = 0.002, respectively); and, 2) hypoxia did not alter the cerebral response to the CPT (P = 0.141 and P = 0.150, respectively). These data highlight that regional differences in cerebrovascular control exist during the CPT.

中文翻译:

全球 REACH 2018:常氧和缺氧冷加压试验期间脑血流速度控制的区域差异

氧气对冷加压试验(CPT)的大脑反应的影响仍然未知。在 13 名参与者中,在等二氧化碳常氧和缺氧 (SpO2 = 85%) CPT 期间测量了血压、大脑中动脉和大脑后动脉血流速度(分别为 MCAv 和 PCAv)。主要发现是:1) 在常氧和缺氧条件下,MCAv 对 CPT 的反应比 PCAv 更大(分别为 P = 0.003 和 P = 0.002);并且,2)缺氧不会改变对 CPT 的大脑反应(分别为 P = 0.141 和 P = 0.150)。这些数据强调了 CPT 期间脑血管控制存在区域差异。
更新日期:2020-12-01
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