Abstract This study aimed to detect the quantitative trait loci (QTL) which affecting the growth traits in some parts of chromosomes 1 of Sanjabi lambs. The study population consisted of six groups of fathers which had an average of 39.17 lambs. Initially, the fathers were genotyped for eight microsatellite markers on chromosome 1, and the offspring of the heterozygote fathers were genotyped. The quantitative traits were the body’s weight at birth, 3, 6, 9, and 12 months, which were corrected for the fixed effects of year of birth, sex, and birth type. QTL search was performed by interval mapping based on a regression model for each cM (Centimorgan) of the chromosomes. In total, one QTL in the 235 cM of chromosome 1 was identified from the beginning of the chromosome in associate with weaning weight. The sire substitution effect for both families was 2.14 kg. The confidence interval estimation of the detected QTL that was estimated using the Bootstrap method was 225 to 238 cM of chromosome 1. This QTL was determined between the MCM137 and MCM130 markers and at a distance of about 9 cM from the MCM137 marker. If this QTL was approved in the next research, it can be used in Marker-assisted selection programs. In this case, more accuracy should be achieved for the evaluation of superior animals.

中文翻译：

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生长第一年数量性状基因座对Sanjabi羔羊1号染色体生长性状的影响

摘要 本研究旨在检测影响Sanjabi羔羊1号染色体部分生长性状的数量性状位点(QTL)。研究人群由六组父亲组成，平均有 39.17 只小羊。最初，父亲对 1 号染色体上的 8 个微卫星标记进行了基因分型，并对杂合子父亲的后代进行了基因分型。数量性状为出生、3、6、9、12个月时的体重，并根据出生年份、性别和出生类型的固定效应进行校正。QTL 搜索是通过基于每个 cM (Centimorgan) 染色体的回归模型的区间作图进行的。总的来说，1号染色体的235cM中的一个QTL从与断奶体重相关的染色体开始被鉴定出来。两个家族的父代替代效应为 2.14 kg。使用 Bootstrap 方法估计的检测到的 QTL 的置信区间估计为 1 号染色体的 225 至 238 cM。该 QTL 是在 MCM137 和 MCM130 标记之间确定的，距离 MCM137 标记约 9 cM。如果该 QTL 在下一次研究中获得批准，则可用于标记辅助选择程序。在这种情况下，对优良动物的评价应该达到更高的准确性。它可用于标记辅助选择程序。在这种情况下，对优良动物的评价应该达到更高的准确性。它可用于标记辅助选择程序。在这种情况下，对优良动物的评价应该达到更高的准确性。