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A “Sugar-Coated” Proton Pump Comes into Focus: High-Resolution Structure of a Human V-ATPase
Molecular Cell ( IF 14.5 ) Pub Date : 2020-11-05 , DOI: 10.1016/j.molcel.2020.10.020
Rebecca A Oot 1 , Stephan Wilkens 1
Affiliation  

In this issue of Molecular Cell, Wang et al. (2020a) present near-atomic resolution cryoEM structures of a proton-pumping vacuolar ATPase from human cells, illuminating the glycosylation of integral subunits and identifying a novel and conserved glycolipid ligand.



中文翻译:

“糖衣”质子泵成为焦点:人类 V-ATPase 的高分辨率结构

在本期分子细胞中,Wang 等人。(2020a) 展示了来自人类细胞的质子泵送液泡 ATP 酶的近原子分辨率冷冻电镜结构,阐明了完整亚基的糖基化并鉴定了一种新型保守的糖脂配体。

更新日期:2020-11-06
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