An uncommon presentation of paraneoplastic limbic encephalitis,Journal of Neuroimmunology

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An uncommon presentation of paraneoplastic limbic encephalitis
Journal of Neuroimmunology ( IF 2.9 ) Pub Date : 2021-01-01 , DOI: 10.1016/j.jneuroim.2020.577437
Yoel Schwartzmann ₁ , Yael Paran ₂ , Orna Aizenstein ₃ , Yifat Alcalay ₄ , Avi Gadoth ₅

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Paraneoplastic limbic encephalitis (PLE) is a rare disease with established diagnostic criteria. We describe a case of an uncommon presentation of PLE in a female who presented with a one- year duration of short-term memory loss and mild behavioral changes who was eventually diagnosed with PLE associated with breast cancer. Our case demonstrates atypical presentation of PLE, with chronic presentation and an uncharacteristic mild neurological symptoms. This case aims to highlight the importance of a diagnostic work up of autoimmune encephalitis in selected cases that does not present with common diagnostic criteria.

中文翻译：

副肿瘤性边缘叶脑炎的罕见表现

副肿瘤性边缘脑炎（PLE）是一种罕见疾病，具有既定的诊断标准。我们描述了一个罕见的 PLE 病例，患者为女性，该患者出现持续一年的短期记忆丧失和轻微的行为改变，最终被诊断为与乳腺癌相关的 PLE。我们的病例显示 PLE 的非典型表现，具有慢性表现和不典型的轻度神经系统症状。本病例旨在强调在不符合共同诊断标准的选定病例中进行自身免疫性脑炎诊断工作的重要性。

更新日期：2021-01-01

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