Abstract In this manuscript the impact of three organic molecules (in the presence and absence of zinc ions) in a more realistic solution medium is presented. The impact of the urinary medium on the morphology of the calcium oxalate monohydrate formed is similar to that seen in the presence of citric acid, the dominant component. The particles formed are relatively flat, rounded particles. In the presence of zinc ions, the particles are little changed with the main change being more rounded particles. The presence of the different organic acids show different impacts for different organics. Ethylenediamintetraacetic acid complexes calcium ions and lowers the supersaturation as a chelator would be expected to. It also impacts the growing crystal changing the morphology. In the case of tartaric acid, adsorption onto critical nuclei and/or growth features leads to incorporation. Finally, the most complex impact was found for maleic acid. Maleic acid interacts with citric acid, inhibiting the citric acid effect. This can be seen in the morphology of particles being similar to those in pure water. The presence of zinc ions generally led to zeta potential values that were closer to zero and therefore would increase the propensity for these particles to coagulate.

中文翻译：

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合成尿液介质中草酸钙结晶：更复杂的溶液介质、有机分子和锌离子的影响

摘要 在这份手稿中，呈现了三种有机分子（存在和不存在锌离子）在更真实的溶液介质中的影响。尿液介质对形成的草酸钙一水合物形态的影响类似于在主要成分柠檬酸存在下所见的影响。形成的颗粒是相对扁平的圆形颗粒。在锌离子的存在下，颗粒变化很小，主要变化是更圆的颗粒。不同有机酸的存在对不同的有机物显示出不同的影响。乙二胺四乙酸络合钙离子并降低过饱和度，正如预期的螯合剂。它还影响生长的晶体改变形态。在酒石酸的情况下，吸附到关键核和/或生长特征上导致掺入。最后，发现了对马来酸的最复杂的影响。马来酸与柠檬酸相互作用，抑制柠檬酸作用。这可以从与纯水中的颗粒形态相似的颗粒形态中看出。锌离子的存在通常会导致 zeta 电位值接近于零，因此会增加这些颗粒凝结的倾向。