Channeling morphogenic signaling gradients intrinsic to intestinal epithelial stem cells, Nikolaev et al. (2020) optimized a three-dimensional microchip perfusion system that augments growth, maturation, and longevity of tubular intestinal enteroids. Reported in Nature, this system may ultimately pave the way to study human intestinal development and pathophysiology, perhaps for therapeutic discovery.

中文翻译：

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流动性的目的：灌注3D开放式支架可改善“小肠”形态发生和寿命

Nikolaev等人，肠道上皮干细胞固有的通道形态发生信号梯度。（2020年）优化了三维微芯片灌注系统，该系统可增强管状肠小肠的生长，成熟和寿命。在《自然》杂志上报道，该系统最终可能为研究人体肠道发育和病理生理学铺平道路，也许是为了发现治疗方法。