Biomineralization is of paramount importance for life on Earth. The delicate balance of physicochemical interactions at the interface between organic and inorganic matter during all stages of biomineralization resembles an extremely high complexity. The coordination of this sophisticated biological machinery and physicochemical scenarios is certainly a wonderful show of nature. Understanding of the biomineralization processes is still far from complete. The recent advances in biomineralization research from the Colloid and Interface Science perspective are reviewed herein. The synergy between this two fields of research is demonstrated. The unique opportunities offered by purposefully designed fluid interfaces, mainly Langmuir monolayers are presented. Biomedical applications of biomineral-based nanostructures are discussed, showing their improved biocompatibility and on-demand delivery features. A brief guide to the array of state-of-the-art experimental techniques for unraveling the mechanisms of biomineralization using fluid interfaces is included. In summary, the fruitful and exciting crossroad between Colloid and Interface Science with Biomineralization is exhibited.

生物矿化对地球上的生命至关重要。在生物矿化的所有阶段，有机物和无机物之间的界面处物理化学相互作用的微妙平衡类似于极高的复杂性。这种复杂的生物机械和物理化学场景的协调无疑是大自然的绝妙表现。对生物矿化过程的了解还远未完成。本文从胶体和界面科学的角度回顾了生物矿化研究的最新进展。这两个研究领域之间的协同作用得到了证明。展示了专门设计的流体界面所提供的独特机会，主要是朗缪尔单层。讨论了基于生物矿物的纳米结构的生物医学应用，显示其改进的生物相容性和按需交付功能。包括使用流体界面解开生物矿化机制的一系列最先进的实验技术的简要指南。总之，展示了胶体和界面科学与生物矿化之间富有成效和令人兴奋的十字路口。