Breast cancer is the most common malignancy among females worldwide. The tumor microenvironment usually prevents effective lymphocyte activation and infiltration, and suppresses infiltrating effector cells, leading to a failure of the host to reject the tumor. CC chemokines play a significant role in inflammation and infection.

中文翻译：

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CCL8/21 作为乳腺癌微环境中潜在预后生物标志物的生物信息学鉴定。

乳腺癌是全球女性中最常见的恶性肿瘤。肿瘤微环境通常会阻止有效的淋巴细胞激活和浸润，并抑制浸润的效应细胞，导致宿主无法排斥肿瘤。CC趋化因子在炎症和感染中起重要作用。