The prevalence of hypertension has increased rapidly in recent years. Currently, increasing attention has been paid to the relationship between hypertension and platelet abnormalities. As a simple and available platelet parameter, platelet distribution width (PDW) can reflect platelet abnormalities and further reflect the risk of thrombotic diseases. However, the views on PDW and hypertension are controversial at present studies. Hence, we aimed to find the associations between PDW and hypertension subtypes in this study. 73469 participants (44665 males and 28804 females) were enrolled. We found that PDW was a risk factor for isolated systolic hypertension (ISH), and the risk of ISH increased with PDW quartiles among women. In men, high PDW might be a risk factor for isolated diastolic hypertension and systolic-diastolic hypertension.

中文翻译：

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男性和女性的血小板分布宽度和高血压亚型之间的不同关联。

近年来，高血压的发病率迅速增加。目前，越来越关注高血压与血小板异常之间的关系。作为简单而可用的血小板参数，血小板分布宽度（PDW）可以反映血小板异常，并进一步反映血栓性疾病的风险。然而，关于PDW和高血压的观点在当前研究中存在争议。因此，我们旨在寻找这项研究中PDW与高血压亚型之间的关联。招募了73469名参与者（男44665，女28804）。我们发现，PDW是孤立性收缩期高血压（ISH）的危险因素，并且女性中PDW四分位数会增加ISH的风险。在男性中，高PDW可能是孤立性舒张期高血压和收缩期舒张期高血压的危险因素。