A new megastigmane glycoside, gangeticoside (1), and three known compounds leonuriside A (2), methyl benzoate 2-O-β-D-glucopyranoside (3), and tortoside A (4) were isolated from the aerial part of Desmodium gangeticum. Their structures were determined by 1D and 2D NMR spectra. The isolated compounds were evaluated for their inhibitory effect on NO production in LPS-stimulated RAW264.7 cells. Among them, compounds 1, 2, and 3 exhibited strong effect with the IC50 values of 22.3, 15.6, 7.3 μM, respectively.

中文翻译：

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来自大叶金钱草的一种新的巨柱花苷葡萄糖苷和其他成分

从 Desmodium gangeticum 地上部分分离出一种新的巨豆苷、gangeticoside (1) 和三种已知化合物 leonuriside A (2)、苯甲酸甲酯 2-O-β-D-吡喃葡萄糖苷 (3) 和 Tortoside A (4) . 它们的结构由一维和二维核磁共振谱确定。评估了分离的化合物对 LPS 刺激的 RAW264.7 细胞中 NO 产生的抑制作用。其中，化合物1、2和3表现出较强的作用，IC50值分别为22.3、15.6、7.3 μM。