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Actigraphy-recorded sleep efficiency and hippocampal volume are related to visual and verbal rate of forgetting in older adults
Aging, Neuropsychology, and Cognition ( IF 1.6 ) Pub Date : 2020-11-03 , DOI: 10.1080/13825585.2020.1842849
Alessandra Lee 1, 2, 3, 4 , Suncica Lah 1 , Samantha Joplin 1, 3 , Carla Haroutonian 1, 2, 3, 4, 5 , Jonathon Pye 1, 2, 3, 4 , Loren Mowszowski 1, 2, 3, 4, 5 , Shantel L Duffy 2, 3, 4, 5 , Sharon L Naismith 1, 2, 3, 4, 5
Affiliation  

ABSTRACT

This study aimed to determine if older adults “at-risk” for dementia (those with MCI or SMC) exhibit accelerated long-term forgetting (ALF) and whether rate of forgetting (RoF) is associated with sleep efficiency, hippocampal volume and demographic/clinical features. Forty-nine “at-risk” participants and eighteen controls underwent examination. Memory was assessed using the Scene Memory Task (SMT) and WMS-III Logical Memory (LM) subtest. Tests were administered at baseline, 24 hours and 2 weeks. While our study did not find ALF in those “at-risk” for dementia, on the SMT, RoF over 24 hours and 2 weeks was negatively correlated with sleep efficiency. For LM, RoF at 2 weeks was moderately associated with left hippocampal volume. Neither visual or verbal RoF was correlated with demographic or clinical variables (age, MMSE, IQ, GDS-15). While ALF was not observed in this sample, our results suggest that visual and verbal forgetting have differential predictors.



中文翻译:

活动记录仪记录的睡眠效率和海马体积与老年人的视觉和语言遗忘率有关

摘要

本研究旨在确定老年人(患有 MCI 或 SMC 的老年人)是否表现出加速的长期遗忘 (ALF) 以及遗忘率 (RoF) 是否与睡眠效率、海马体积和人口统计相关。临床表现。49 名“有风险”的参与者和 18 名对照接受了检查。使用场景记忆任务 (SMT) 和 WMS-III 逻辑记忆 (LM) 子测试评估记忆。在基线、24 小时和 2 周时进行测试。虽然我们的研究没有在痴呆症“高危”人群中发现 ALF,但在 SMT 上,超过 24 小时和 2 周的 RoF 与睡眠效率呈负相关。对于 LM,2 周时的 RoF 与左侧海马体积中度相关。视觉或语言 RoF 均与人口统计学或临床变量(年龄、MMSE、IQ、GDS-15)无关。

更新日期:2020-11-03
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