Biomarkers reflecting the course of patients suffering from anti‐N‐methyl‐D‐aspartate receptor encephalitis (anti‐NMDARE) are urgently needed. Neurofilament light chains (NfL) have been studied as potential markers for neuroaxonal injury mainly in neuroinflammatory diseases, but so far there have been only in a few small reports on anti‐NMDARE. We aimed to compare the longitudinal course of cerebrospinal fluid (CSF)‐NfL levels and anti‐N‐methyl‐D‐aspartate receptor (anti‐NMDAR) antibodies with clinical parameters in six patients with anti‐NMDARE.

中文翻译：

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抗N-甲基-D-天冬氨酸受体脑炎脑脊液神经丝光的纵向测量

迫切需要反映抗 N-甲基-D-天冬氨酸受体脑炎（抗 NMDARE）患者病程的生物标志物。神经丝轻链 (NfL) 已被研究作为神经轴突损伤的潜在标志物，主要是在神经炎症性疾病中，但到目前为止，只有少数关于抗 NMDARE 的报道。我们旨在比较 6 名抗 NMDARE 患者的脑脊液 (CSF)-NfL 水平和抗 N-甲基-D-天冬氨酸受体 (抗 NMDAR) 抗体与临床参数的纵向过程。