There is an increasing interest in determining the concentration of furanic compounds naturally formed in food aqueous matrices, by in situ, fast and low-cost methods. A sensor presenting such characteristics is here proposed, and characterized. It is based on a molecularly imprinted polymer (MIP) as a receptor with electrochemical transduction on a screen printed cell (SPC). The molecularly imprinted polymer has been developed for a particular furanic derivative, 2-furaldehyde (2-FAL). The detection bases on the reduction of 2-FAL selectively adsorbed on the polymer layer in contact with the working electrode. The polymer layer is simply formed by in situ polymerization, directly over the SPC and it was characterized by IR, SEM and electrochemical methods. Even if based on an easy and fast preparation procedure, the layer sufficiently adheres to the cell surface giving a reusable sensor. Square wave voltammetry (SWV) was applied as the signal acquisition method. The sensor performance in aqueous solution (NaCl 0.1 M) was tested, obtaining that the dose-response curve is fitted by the Langmuir adsorption isotherm. The sensitivity, and so the limit of detection, were noticeably improved by a chemometric approach based on the Design of experiment method. (optimized conditions: Estep = 0.03 V, Epulse = 0.066 V, f = 31 s-1). In water solution at pH around neutrality the dynamic range was from about 50 μM to 20 mM. Similar results were obtained for a white wine containing 12% ethanol, which has been considered as a typical example of beverage possibly containing furhaldehydes. The higher limit of quantification can be modulated by the amount of MIP deposited, while the lower detection limit by the conditions of the electrochemical measurement.

中文翻译：

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一种基于 MIP 的低成本电化学传感器，用于检测饮料中的 2-糠醛

通过原位、快速和低成本的方法确定食品水性基质中天然形成的呋喃化合物的浓度越来越受到关注。这里提出并表征了具有这种特性的传感器。它基于分子印迹聚合物 (MIP) 作为受体，在丝网印刷电池 (SPC) 上进行电化学转导。分子印迹聚合物已开发用于特定的呋喃衍生物 2-呋喃醛 (2-FAL)。检测基于选择性吸附在与工作电极接触的聚合物层上的 2-FAL 的减少。聚合物层简单地通过原位聚合形成，直接在 SPC 上，并通过 IR、SEM 和电化学方法对其进行表征。即使基于简单快速的准备程序，该层充分粘附到细胞表面，提供可重复使用的传感器。方波伏安法（SWV）被用作信号采集方法。测试了传感器在水溶液 (NaCl 0.1 M) 中的性能，得出剂量响应曲线由朗缪尔吸附等温线拟合。基于实验设计方法的化学计量学方法显着提高了灵敏度和检测限。（优化条件：Estep = 0.03 V，Epulse = 0.066 V，f = 31 s-1）。在 pH 值接近中性的水溶液中，动态范围为约 50 μM 至 20 mM。含有 12% 乙醇的白葡萄酒也得到了类似的结果，这被认为是可能含有糠醛的饮料的典型例子。量化的上限可以通过沉积的 MIP 量进行调节，