An 8-mo-old male African pygmy hedgehog was anorectic and ataxic; physical examination revealed tetraparesis and a gangrenous left hindlimb. Analgesic and supportive care were administered, but the animal died 3 d after presentation. Postmortem examination revealed a histiocytic sarcoma in a mesenteric lymph node with metastasis to several organs, multifocal vacuolation in the cerebral and cerebellar white matter, and a meningioma in the left lateral ventricle. We diagnosed wobbly hedgehog syndrome (WHS) with disseminated histiocytic sarcoma and lateral ventricular meningioma. Ventricular meningioma, a rare neoplasm in veterinary and human patients, has not been reported previously in hedgehogs, to our knowledge. The neurologic signs in our case were probably caused by the WHS-related vacuolar lesions and are consistent with those of reported WHS cases. Duration of illness was shorter than is typical of WHS cases, which might be related to the disseminated histiocytic sarcoma. Clinical relevance of the lateral ventricular meningioma was not evident because the ventricular mass was localized and not invasive.

一只 8 个月大的雄性非洲侏儒刺猬厌食和共济失调；体格检查显示四肢瘫痪和左后肢坏疽。给予镇痛和支持治疗，但动物在就诊后 3 天死亡。尸检显示肠系膜淋巴结组织细胞肉瘤转移至多个器官，大脑和小脑白质多灶性空泡，左侧脑室脑膜瘤。我们诊断出具有播散性组织细胞肉瘤和侧脑室脑膜瘤的摇摆刺猬综合征 (WHS)。据我们所知，脑室脑膜瘤是兽医和人类患者中的一种罕见肿瘤，以前在刺猬中没有报道过。我们病例的神经系统体征可能是由 WHS 相关的空泡病变引起的，与报告的 WHS 病例一致。病程比典型的 WHS 病例短，这可能与播散性组织细胞肉瘤有关。侧脑室脑膜瘤的临床相关性不明显，因为脑室肿块是局部的，不是侵入性的。