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IRAK4 degrader to take on innate immunity
Nature Biotechnology ( IF 33.1 ) Pub Date : 2020-11-03 , DOI: 10.1038/s41587-020-0724-8 Asher Mullard
Nature Biotechnology ( IF 33.1 ) Pub Date : 2020-11-03 , DOI: 10.1038/s41587-020-0724-8 Asher Mullard
Interest in anti-inflammatory IRAK4 signaling is ramping up, as small-molecule ‘degraders’ that bind both the kinase and E3 ubiquitin ligases prepare to take on traditional kinase inhibitors.
中文翻译:
IRAK4降解剂具有先天免疫力
随着结合激酶和E3泛素连接酶的小分子“降解剂”准备采用传统的激酶抑制剂,人们对抗炎IRAK4信号的兴趣正在增加。
更新日期:2020-11-03
中文翻译:
IRAK4降解剂具有先天免疫力
随着结合激酶和E3泛素连接酶的小分子“降解剂”准备采用传统的激酶抑制剂,人们对抗炎IRAK4信号的兴趣正在增加。