Fetal mitochondrial DNA in maternal plasma in surrogate pregnancies: Detection and topology,Prenatal Diagnosis

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Fetal mitochondrial DNA in maternal plasma in surrogate pregnancies: Detection and topology
Prenatal Diagnosis ( IF 3 ) Pub Date : 2020-11-02 , DOI: 10.1002/pd.5860
Mary-Jane L Ma _{1,

2} , Sergey Yakovenko _{3,

4} , Haiqiang Zhang _{1,

2} , Suk Hang Cheng _{1,

2} , Valentina Apryshko ₃ , Alex Zhavoronkov ₅ , Peiyong Jiang _{1,

2} , K C Allen Chan _{1,

2} , Rossa W K Chiu _{1,

2} , Y M Dennis Lo _{1,

2}

Affiliation

Due to the maternally‐inherited nature of mitochondrial DNA (mtDNA), there is a lack of information regarding fetal mtDNA in the plasma of pregnant women. We aim to explore the presence and topologic forms of circulating fetal and maternal mtDNA molecules in surrogate pregnancies.

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