The use of photosensitizers (PSs) in cancer therapy opened new avenues for developing minimally‐invasive treatment of cancer. However, problems related to lack of biocompatibility and tumor targeting of many photosensitizers limited their clinical use for many years. Tailor‐made polymeric nanoparticles can significantly enhance the biocompatibility of the photosensitizers, achieve high cellular internalization and prolonged blood circulation. Further, attachement of the photosensitizer to bifunctional polymeric chains can be used for building novel nano‐constructions such as combination therapy and image‐guided therapy. This review describes the innovations pertaining to polymeric drug delivery systems of laser‐based cancer therapeutics as disclosed in recent literature. Phthalocyanines were considered a model of photosensitizers and photodynamic therapy (PDT) as a model of phototherapy. Interestingly, these models are applicable to other biomedical photoreceptors such as porphyrins, Chlorin e6, gold nanoparticles, quantum dots, carbon dots, etc.

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用于增强光动力癌症治疗的聚合物：酞菁类作为光敏剂模型

在癌症治疗中使用光敏剂（PSs）为开发微创治疗癌症开辟了新途径。然而，与许多光敏剂缺乏生物相容性和肿瘤靶向性有关的问题限制了它们多年的临床应用。量身定制的聚合物纳米颗粒可以显着增强光敏剂的生物相容性，实现高度的细胞内在化和延长血液循环。此外，光敏剂与双功能聚合物链的连接可用于构建新型纳米构造，例如联合疗法和图像引导疗法。这篇综述描述了与基于激光的癌症治疗药物的聚合物药物递送系统有关的创新，如最近的文献所披露。酞菁被认为是光敏剂的模型，而光动力疗法（PDT）被视为光疗法的模型。有趣的是，这些模型适用于其他生物医学感光器，例如卟啉，氯绿素e6，金纳米颗粒，量子点，碳点等。