We performed a prospective multicenter case‐control study to explore the association between ulnar neuropathy at elbow (UNE) and body and elbow anthropometric measures, demographic and lifestyle factors, and comorbidities. Cases and controls were consecutively enrolled among subjects admitted to four electromyography labs. UNE diagnosis was made on clinical and neurographic findings. The control group included all other subjects without signs/symptoms of ulnar neuropathy and with normal ulnar nerve neurography. Anthropometric measurements included weight, height, waist, hip circumferences, and external measures of elbow using a caliper. The participants filled in a self‐administered questionnaire on personal characteristics, lifestyle factors, and medical history. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) by fitting unconditional logistic regression models adjusted by center and education level. We enrolled 220 cases (males 61.8%; mean age 51.7 years) and 460 controls (47.4% males; mean age 47.8 years). At multivariable analysis, UNE was associated to male gender (OR = 2.4, 95%CI = 1.6‐3.7), smoking habits (>25 pack‐years (OR = 2.3, 95%CI = 1.3‐4.1), body mass index (OR = 1.05, 95%CI 1.01‐1.10), polyneuropathies (OR = 4.1, 95%CI 1.5‐11.5), and leaning with flexed elbow on a table/desk (OR = 1.5, 95%CI 1.0‐2.2). Cubital groove width (CGW) turned out to be negatively associated with UNE (OR = 0.80, 95%CI = 0.74‐0.85). Our study suggests that some personal factors especially anthropometric measures of the elbow may play a role in UNE pathogenesis as the measures of wrist in CTS. We demonstrated that for each millimeter of smaller CGW the risk of idiopathic UNE increases of 25%.

中文翻译：

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肘部尺神经病变的合并症、人体测量学、人口统计学和生活方式危险因素：病例对照研究

我们进行了一项前瞻性多中心病例对照研究，以探讨肘部尺神经病变 (UNE) 与身体和肘部人体测量指标、人口统计学和生活方式因素以及合并症之间的关联。病例和对照被连续纳入四个肌电图实验室的受试者中。UNE 诊断是根据临床和神经学检查结果做出的。对照组包括没有尺神经病变的体征/症状和具有正常尺神经神经造影术的所有其他受试者。人体测量包括体重、身高、腰围、臀围和使用卡尺测量肘部的外部测量值。参与者填写了一份关于个人特征、生活方式因素和病史的自我管理问卷。我们通过拟合由中心和教育水平调整的无条件逻辑回归模型来估计优势比 (OR) 和 95% 置信区间 (CI)。我们招募了 220 个病例（男性 61.8%；平均年龄 51.7 岁）和 460 个对照（男性 47.4%；平均年龄 47.8 岁）。在多变量分析中，UNE 与男性（OR = 2.4，95%CI = 1.6-3.7）、吸烟习惯（>25 包年（OR = 2.3，95%CI = 1.3-4.1）、体重指数（ OR = 1.05，95%CI 1.01-1.10），多发性神经病（OR = 4.1，95%CI 1.5-11.5），弯曲肘部靠在桌子/书桌上（OR = 1.5，95%CI 1.0-2.2）。结果证明凹槽宽度 (CGW) 与 UNE 呈负相关（OR = 0.80，95%CI = 0.74-0.85）。我们的研究表明，一些个人因素，尤其是肘部的人体测量指标可能在 UNE 发病机制中发挥作用。在 CTS 中的手腕。