Abstract Two-dimensional molybdenum disulphide nanosheets (2D-MoS2) were prepared by liquid-phase exfoliation and used to modify screen-printed carbon electrodes (SPCE), in order to develop an electrochemical sensor for the simultaneous determination of dopamine (DA) and tyrosine (Tyr) in presence of uric acid (UA). To demonstrated the layered morphology, the synthesized molybdenum disulphide nanostructures, have been characterized by Raman and SEM techniques in both liquid dispersion and after deposition on SPCE. The performances of the 2D-MoS2-SPCE electrode have been tested and optimized in terms of sensitivity, reaching high sensitivity values of 1044 μA mM-1 cm−2 for DA and 321 μA mM-1 cm−2 for Tyr, selectivity against UA and high stability. The simultaneous detection of these biomolecules is the first study so far reported with the use of 2D-MoS2-based sensors. The promising characteristics of the developed electrodes suggest 2D-MoS2 as a versatile, low cost and easy to produce material for the next generation of electrochemical sensors of a variety of important biomolecules.

中文翻译：

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2D-MoS2纳米片修饰丝网印刷碳电极在尿酸存在下同时选择性测定多巴胺和酪氨酸

摘要 通过液相剥离法制备二维二硫化钼纳米片 (2D-MoS2) 并用于修饰丝网印刷碳电极 (SPCE)，以开发同时测定多巴胺 (DA) 和酪氨酸的电化学传感器。 (Tyr) 在尿酸 (UA) 存在下。为了证明层状形态，合成的二硫化钼纳米结构已通过拉曼和 SEM 技术在液体分散体和在 SPCE 上沉积后进行表征。2D-MoS2-SPCE 电极的性能已经在灵敏度方面进行了测试和优化，DA 的灵敏度值达到 1044 μA mM-1 cm-2，Tyr 的灵敏度值达到 321 μA mM-1 cm-2，对 UA 具有选择性和高稳定性。这些生物分子的同时检测是迄今为止使用基于 2D-MoS2 的传感器报道的第一项研究。所开发电极的有前途的特性表明 2D-MoS2 是一种多功能、低成本且易于生产的材料，可用于各种重要生物分子的下一代电化学传感器。