A 50-year-old male western gorilla (Gorilla gorilla) presented with severe bradypragia, anorexia and vomiting. Despite continuous administration of antiphlogistic analgesic drugs and supportive care, the animal died and was submitted for post-mortem examination. Macroscopically, a large mass was located in the duodenum. The mucosal surface of the duodenum was irregular and thickened, and the lumen narrowed. The duodenal lesion was identified as a tubular adenocarcinoma and the neoplastic cells were strongly positive for cytokeratin AE1/AE3, cytokeratin 7, cytokeratin 19 and mucin-6 protein. Ultrastructurally, the apical cytoplasm of neoplastic cells had electron dense granules and apical microvilli. This is the first reported case of Brunner's gland adenocarcinoma in a gorilla.

一只50岁的雄性西部大猩猩（Gorilla gorilla）出现严重的动作迟缓、厌食和呕吐。尽管持续服用消炎镇痛药和支持治疗，该动物仍死亡并进行尸检。宏观上，十二指肠内有一大肿块。十二指肠黏膜表面不规则增厚，管腔变窄。十二指肠病变被鉴定为管状腺癌，肿瘤细胞的细胞角蛋白 AE1/AE3、细胞角蛋白 7、细胞角蛋白 19 和粘蛋白 6 蛋白呈强阳性。超微结构，肿瘤细胞顶端胞质有电子致密颗粒和顶端微绒毛。这是大猩猩布伦纳腺癌的首例报道。