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Synthesis of 8-oxa-2-azaspiro[4.5]decane
Russian Chemical Bulletin ( IF 1.7 ) Pub Date : 2020-10-01 , DOI: 10.1007/s11172-020-2994-1
V. A. Ogurtsov , O. A. Rakitin

A convenient synthesis of new 8-oxa-2-azaspiro[4.5]decane from commercially available reagents based on tetrahydropyran-4-carbonitrile and 1-bromo-2-fluoroethane has been developed. This compound is promising for the production of important biologically active compounds.

中文翻译:

8-氧杂-2-氮杂螺[4.5]癸烷的合成

已经开发了一种基于四氢吡喃-4-甲腈和 1-溴-2-氟乙烷的市售试剂方便地合成新的 8-oxa-2-azaspiro[4.5] 癸烷。该化合物有望用于生产重要的生物活性化合物。
更新日期:2020-10-01
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