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A mutation in SLC20A2 (c.C1849T) promotes proliferation while inhibiting hypertrophic differentiation in ATDC5 chondrocytes.
Bone & Joint Research ( IF 4.7 ) Pub Date : 2020-11-3 , DOI: 10.1302/2046-3758.911.bjr-2020-0112.r1 YiQiang Li 1 , XueMei Lin 1 , MingWei Zhu 1 , FuXing Xun 1 , JingChun Li 1 , Zhe Yuan 1 , YanHan Liu 1 , HongWen Xu 1
Bone & Joint Research ( IF 4.7 ) Pub Date : 2020-11-3 , DOI: 10.1302/2046-3758.911.bjr-2020-0112.r1 YiQiang Li 1 , XueMei Lin 1 , MingWei Zhu 1 , FuXing Xun 1 , JingChun Li 1 , Zhe Yuan 1 , YanHan Liu 1 , HongWen Xu 1
Affiliation
This study aimed to investigate the effect of solute carrier family 20 member 2 (SLC20A2) gene mutation (identified from a hereditary multiple exostoses family) on chondrocyte proliferation and differentiation.
中文翻译:
SLC20A2 (c.C1849T) 的突变可促进 ATDC5 软骨细胞增殖,同时抑制肥大分化。
本研究旨在探讨溶质载体家族20成员2 ( SLC20A2 )基因突变(来自遗传性多发性外生骨疣家族)对软骨细胞增殖和分化的影响。
更新日期:2020-11-04
中文翻译:
SLC20A2 (c.C1849T) 的突变可促进 ATDC5 软骨细胞增殖,同时抑制肥大分化。
本研究旨在探讨溶质载体家族20成员2 ( SLC20A2 )基因突变(来自遗传性多发性外生骨疣家族)对软骨细胞增殖和分化的影响。