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Microfluidic devices powered by integrated elasto-magnetic pumps
Lab on a Chip ( IF 6.1 ) Pub Date : 2020-10-23 , DOI: 10.1039/d0lc00935k Jacob L Binsley 1 , Elizabeth L Martin 1 , Thomas O Myers 2 , Stefano Pagliara 3 , Feodor Y Ogrin 1
Lab on a Chip ( IF 6.1 ) Pub Date : 2020-10-23 , DOI: 10.1039/d0lc00935k Jacob L Binsley 1 , Elizabeth L Martin 1 , Thomas O Myers 2 , Stefano Pagliara 3 , Feodor Y Ogrin 1
Affiliation
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We show how an asymmetric elasto-magnetic system provides a novel integrated pumping solution for lab-on-a-chip and point of care devices. This monolithic pumping solution, inspired by Purcell's 3-link swimmer, is integrated within a simple microfluidic device, bypassing the requirement of external connections. We experimentally prove that this system can provide tuneable fluid flow with a flow rate of up to 600 μL h−1. This fluid flow is achieved by actuating the pump using a weak, uniform, uniaxial, oscillating magnetic field, with field amplitudes in the range of 3–6 mT. Crucially, the fluid flow can be reversed by adjusting the driving frequency. We experimentally prove that this device can successfully operate on fluids with a range of viscosities, where pumping at higher viscosity correlates with a decreasing optimal driving frequency. The fluid flow produced by this device is understood here by examining the non-reciprocal motion of the elasto-magnetic component. This device has the capability to replace external pumping systems with a simple, integrated, lab-on-a-chip component.
中文翻译：
由集成弹磁泵驱动的微流体装置
我们展示了非对称弹磁系统如何为芯片实验室和护理点设备提供新颖的集成泵解决方案。这种整体泵送解决方案的灵感来自于 Purcell 的 3 连杆游泳器，它集成在一个简单的微流体设备中，绕过了外部连接的要求。我们通过实验证明该系统可以提供流量高达600 μL h -1的可调流体流量。这种流体流动是通过使用弱、均匀、单轴振荡磁场驱动泵来实现的，磁场幅度在 3-6 mT 范围内。至关重要的是，可以通过调节驱动频率来反转流体流动。我们通过实验证明，该设备可以成功地对一系列粘度的流体进行操作，其中较高粘度的泵送与最佳驱动频率的降低相关。这里通过检查弹磁部件的非往复运动来理解该装置产生的流体流动。该器件能够用简单的集成芯片实验室组件取代外部泵系统。
更新日期：2020-11-03
中文翻译：
由集成弹磁泵驱动的微流体装置
我们展示了非对称弹磁系统如何为芯片实验室和护理点设备提供新颖的集成泵解决方案。这种整体泵送解决方案的灵感来自于 Purcell 的 3 连杆游泳器，它集成在一个简单的微流体设备中，绕过了外部连接的要求。我们通过实验证明该系统可以提供流量高达600 μL h -1的可调流体流量。这种流体流动是通过使用弱、均匀、单轴振荡磁场驱动泵来实现的，磁场幅度在 3-6 mT 范围内。至关重要的是，可以通过调节驱动频率来反转流体流动。我们通过实验证明，该设备可以成功地对一系列粘度的流体进行操作，其中较高粘度的泵送与最佳驱动频率的降低相关。这里通过检查弹磁部件的非往复运动来理解该装置产生的流体流动。该器件能够用简单的集成芯片实验室组件取代外部泵系统。
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