Enoxacin, as the broad-spectrum antibacterial activity antibiotics, has been widely used in treatment of bacterial diseases in animals and humans around the world. The extensive use of enoxacin in healthcare has also caused increasingly serious environmental risk as a matter of course. In this work, enoxacin imprinted poly (vinylidene fluoride) (PVDF) composite membranes (EIPCMs) were developed by strategy of surface grafting beta-cyclodextrin ([Formula: see text]-CD) for the improved hydrophilic and antifouling properties of the basal membrane. PVDF membrane was prepared by phase inversion method, and [Formula: see text]-CD was grafted onto the surface after hydroxyl groups modification. The effects of adding amount of [Formula: see text]-CD on performance of basal membranes were systematically examined. Further, the specific recognition sites were fabricated via sol–gel surface imprinting method using 3-aminopropyltriethoxysilane (APTES) and tetraethoxysilane (TEOS) as functional monomer and cross-linker, respectively. The specific adsorption and permeation experiments were investigated and explored the separation performance and mechanism of EIPCM. The results indicated that the as-prepared EIPCMs not only exhibited highly favorable features and high rebinding strength (31.25[Formula: see text]mg g[Formula: see text], but also possessed superior selective performance toward enoxacin (imprinted factor [Formula: see text] is 3.15). Furthermore, in order to investigate the practical applications of EIPCMs, the adsorption experiments were carried out using environmental sewage. The work developed here shows great potential for further applications in selective recognition and separation antibiotics pollution from the environment.

中文翻译：

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加速基于β-CD-PVDF的分子印迹纳米复合膜的选择性分离设计：一种表面功能单体导向策略

依诺沙星作为广谱抗菌活性抗生素，已在世界各地广泛用于治疗动物和人类的细菌性疾病。依诺沙星在医疗保健中的广泛使用也理所当然地造成了日益严重的环境风险。在这项工作中，通过表面接枝β-环糊精（[分子式：见正文]-CD）的策略开发了依诺沙星印迹聚（偏二氟乙烯）（PVDF）复合膜（EIPCM），以提高基膜的亲水性和防污性。 . 采用反相法制备PVDF膜，在表面进行羟基改性后接枝[分子式：见正文]-CD。系统考察了[分子式：见正文]-CD的添加量对基底膜性能的影响。进一步，具体的识别位点是通过溶胶-凝胶表面印迹法制造的，分别使用 3-氨基丙基三乙氧基硅烷 (APTES) 和四乙氧基硅烷 (TEOS) 作为功能单体和交联剂。研究了特定的吸附和渗透实验，探索了EIPCM的分离性能和机理。结果表明，所制备的EIPCMs不仅表现出良好的特性和高再结合强度（31.25[公式：见正文]mg g[公式：见正文]，而且对依诺沙星（印迹因子[公式：见正文] 是 3.15). 此外，为了研究 EIPCMs 的实际应用，使用环境污水进行了吸附实验。