Rehabilitation of major mandibular defects after tumor resection has become a serious challenge for surgeons. In this research, four various models were designed to repair a critical mandibular lateral defect. Biomechanical behavior of the models was assessed by Finite Element Method. These models are including Fibular-Free Flap (FFF), Customized Prosthesis (CP), Tray Implant without Bone Graft (TI-wo-BG), and Tray Implant with Bone Graft (TI-w-BG). FFF is a subset of microvascular free flap technique in which some segments of patient’s fibula bone are used to restore mandibular defects. CP is a hollow and light prosthesis which is fabricated using Additive Manufacturing technology from Ti alloy powder. TI-wo-BG is similar to a crib which is designed according to the geometry of the patient’s mandible. TI-w-BG, in fact, is a TI-wo-BG which is filled with small cortico-cancellous chips in order to benefit potential profit of bone grafting. The chewing operation and loading on the mandible was simulated considering the three mandibular muscular forces including masseter, medial pterygoid, and temporalis.The result of FEM analysis of TI-wo-BG and TI-w-BG showed that in both models, screw number 6 endured a strain of 5684 and 2852[Formula: see text][Formula: see text]m/m which exceeded pathological and mild overload risk, respectively. This may increase the probability of screw loosening and system failure. The results proved the stability of the FFF and CP models. In addition, it can be concluded that stress and strain on the screw’s interfaces can decrease by improving the plate and increasing the friction at the interface of plate, bone and screw.

中文翻译：

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使用有限元方法通过不同模型重建广泛下颌骨缺损的生物力学评价

肿瘤切除后主要下颌骨缺损的修复已成为外科医生面临的严峻挑战。在这项研究中，设计了四种不同的模型来修复严重的下颌侧向缺损。通过有限元方法评估模型的生物力学行为。这些模型包括无腓骨皮瓣 (FFF)、定制假体 (CP)、不带骨移植的托盘植入物 (TI-wo-BG) 和带骨移植物的托盘植入物 (TI-w-BG)。FFF 是微血管游离皮瓣技术的一个子集，其中患者腓骨的某些部分用于修复下颌骨缺损。CP 是一种中空轻质假体，采用钛合金粉末的增材制造技术制造。TI-wo-BG 类似于根据患者下颌骨几何形状设计的婴儿床。TI-w-BG，事实上，是一种 TI-wo-BG，其中填充了小的皮质松质芯片，以利于骨移植的潜在利润。考虑咬肌、翼内肌和颞肌三种肌肉力量模拟下颌的咀嚼操作和负荷。TI-wo-BG和TI-w-BG的有限元分析结果表明，在两个模型中，螺钉数6 株经受了 5684 和 2852[公式：见正文][公式：见正文]m/m 的应变，分别超过了病理和轻度超负荷风险。这可能会增加螺丝松动和系统故障的可能性。结果证明了FFF和CP模型的稳定性。此外，可以得出结论，通过改进钢板和增加钢板、骨和螺钉界面处的摩擦力，可以减少螺钉界面上的应力和应变。