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Artichoke extracts in cancer therapy: do the extraction conditions affect the anticancer activity?
Future Journal of Pharmaceutical Sciences ( IF 3.4 ) Pub Date : 2020-10-31 , DOI: 10.1186/s43094-020-00088-0
Heba H. Sokkar , Ahmed S. Abo Dena , Noha Ahmed Mahana , Abeer Badr

Artichoke is an edible plant that is grown in the Mediterranean region and is known for its antimicrobial, antifungal, antibacterial, antioxidant and anticancer activities. Different artichoke extraction methods can impressively affect the nature as well as the yield of the extracted components. The different methods of artichoke extraction and the influence of the extraction conditions on the extraction efficiency are summarized herein. In addition, cancer causalities and hallmarks together with the molecular mechanisms of artichoke active molecules in cancer treatment are also discussed. Moreover, a short background is given on the common types of cancer that can be treated with artichoke extracts as well as their pathogenesis. A brief discussion of the previous works devoted to the application of artichoke extracts in the treatment of these cancers is also given. This review article covers the extraction methods, composition, utilization and applications of artichoke extracts in the treatment of different cancers.

中文翻译:

朝鲜蓟提取物在癌症治疗中的作用:提取条件是否会影响抗癌活性?

朝鲜蓟是一种可食用的植物,生长在地中海地区,以其抗菌,抗真菌,抗菌,抗氧化和抗癌作用而闻名。不同的朝鲜蓟提取方法会显着影响提取成分的性质和收率。本文总结了朝鲜蓟的不同提取方法以及提取条件对提取效率的影响。此外,还讨论了朝鲜蓟活性分子在癌症治疗中的因果关系和标志,以及其分子机制。此外,简要介绍了可以用朝鲜蓟提取物治疗的常见癌症类型及其发病机理。还简要讨论了以前的工作,这些工作致力于朝鲜蓟提取物在这些癌症的治疗中的应用。这篇综述文章涵盖了朝鲜蓟提取物在不同癌症治疗中的提取方法,组成,用途和应用。
更新日期:2020-11-02
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