当前位置: X-MOL 学术Chem. Rev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
Chemical Reviews ( IF 51.4 ) Pub Date : 2020-10-30 , DOI: 10.1021/acs.chemrev.0c00663
Roy Weinstain 1 , Tomáš Slanina 2 , Dnyaneshwar Kand 1 , Petr Klán 3
Affiliation  

Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable) protecting groups (PPGs), also known as caged or photocaged compounds, are used to enable non-invasive spatiotemporal photochemical control over the release of species of interest. Recent years have seen the development of PPGs activatable by biologically and chemically benign visible and near-infrared (NIR) light. These long-wavelength-absorbing moieties expand the applicability of this powerful method and its accessibility to non-specialist users. This review comprehensively covers organic and transition metal-containing photoactivatable compounds (complexes) that absorb in the visible- and NIR-range to release various leaving groups and gasotransmitters (carbon monoxide, nitric oxide, and hydrogen sulfide). The text also covers visible- and NIR-light-induced photosensitized release using molecular sensitizers, quantum dots, and upconversion and second-harmonic nanoparticles, as well as release via photodynamic (photooxygenation by singlet oxygen) and photothermal effects. Release from photoactivatable polymers, micelles, vesicles, and photoswitches, along with the related emerging field of photopharmacology, is discussed at the end of the review.

中文翻译:


可见光到近红外光激活释放:从小分子到纳米材料



可光激活(或者光可去除、光可释放或光可裂解)保护基团(PPG),也称为笼状或光笼状化合物,用于实现对感兴趣物种释放的非侵入性时空光化学控制。近年来,可通过生物和化学良性可见光和近红外 (NIR) 光激活的 PPG 得到了发展。这些长波长吸收部分扩展了这种强大方法的适用性及其对非专业用户的可及性。本综述全面涵盖了有机和含过渡金属的光活化化合物(配合物),它们在可见光和近红外范围内吸收,释放各种离去基团和气体递质(一氧化碳、一氧化氮和硫化氢)。该文本还涵盖了使用分子敏化剂、量子点、上转换和二次谐波纳米粒子引起的可见光和近红外光诱导的光敏释放,以及通过光动力(单线态氧的光氧化)和光热效应进行的释放。综述的最后讨论了光活化聚合物、胶束、囊泡和光开关的释放,以及相关的新兴光药理学领域。
更新日期:2020-12-23
down
wechat
bug