Abstract

Objective

The increased use of online pharmacy services in the midst of the COVID-19 pandemic provides an important backdrop against which to examine the role of neurocognitive functions in health-related Internet navigation skills among persons with chronic medical conditions, such as HIV disease. Prospective memory (PM) is reliably impaired in HIV disease and is related to laboratory-based measures of medication management capacity in other populations. This study examined whether PM shows veridicality in relationship to online pharmacy navigation skills in persons with HIV disease.

Method

Participants included 98 persons with HIV disease age 50 and older who completed the Cambridge Prospective Memory Test (CAMPROMPT) and the Medication-Management Test-Revised (MMT-R) as part of a neuropsychological study. Participants also completed the Test of Online Pharmacy Skills (TOPS), which required them to navigate a simulated, experimenter-controlled online pharmacy to perform several naturalistic tasks (e.g., refill an existing prescription).

Results

Lower PM had medium associations with poorer MMT-R and TOPS accuracy scores that were not better explained by other neurocognitive functions. The association between PM and TOPS accuracy was driven by errors of omission and did not vary meaningfully based on whether the intention was cued by time or an event.

Conclusions

These data suggest that PM cue detection processes show veridicality with online pharmacy navigation skills. Future studies might examine the benefits of PM-based strategies (e.g., salient prompts) in supporting online health navigation skills in populations that experience clinically impactful PM failures.

中文翻译：

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在线药房导航技能与 HIV 疾病的前瞻记忆相关

摘要

客观的

在 COVID-19 大流行期间，越来越多地使用在线药房服务提供了一个重要的背景，在此背景下，可以检查神经认知功能在患有慢性疾病（如 HIV 疾病）的人群中与健康相关的互联网导航技能中的作用。前瞻记忆 (PM) 在 HIV 疾病中确实受损，并且与其他人群中基于实验室的药物管理能力测量相关。本研究检查 PM 是否显示与 HIV 感染者的在线药房导航技能相关的真实性。

方法

参与者包括 98 名 50 岁及以上的 HIV 患者，他们完成了剑桥前瞻性记忆测试 (CAMPROMPT) 和药物管理测试修订版 (MMT-R)，作为神经心理学研究的一部分。参与者还完成了在线药房技能测试 (TOPS)，这要求他们在模拟的、由实验者控制的在线药房中导航，以执行多项自然任务（例如，重新填写现有处方）。

结果

较低的 PM 与较差的 MMT-R 和 TOPS 准确度分数具有中等关联，其他神经认知功能无法更好地解释这些分数。PM 和 TOPS 准确性之间的关联是由遗漏错误驱动的，并且不会根据意图是由时间还是事件提示而产生有意义的变化。

结论

这些数据表明 PM 提示检测过程显示在线药房导航技能的真实性。未来的研究可能会检查基于 PM 的策略（例如，突出提示）在支持经历有临床影响的 PM 失败人群的在线健康导航技能方面的好处。