The history of immunisation is full of heroes but also full of villains, and our successes are tempered by tragedies. Despite the urgent need for a vaccine against SARS-CoV-2, we should not neglect the lessons of history. These include ethical issues relating to vaccine safety, such as the possible risks of vaccine-induced enhancement witnessed with dengue vaccine in the Philippines, and how our decisions may be represented by the anti-vaxx movement.

中文翻译：

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历史告诉我们什么有关疫苗和大流行的知识

免疫接种的历史充满了英雄，但也充满了反派，我们的成功受到悲剧的影响。尽管迫切需要针对SARS-CoV-2的疫苗，但我们不应忽视历史教训。这些问题包括与疫苗安全性相关的道德问题，例如在菲律宾目睹的登革热疫苗可能导致疫苗引起的疫苗增强风险，以及反vaxx运动如何代表我们的决定。