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Photoinactivation of the Coronavirus Surrogate phi6 by Visible Light
Photochemistry and Photobiology ( IF 2.6 ) Pub Date : 2020-11-21 , DOI: 10.1111/php.13352
Petra Vatter 1 , Katharina Hoenes 1 , Martin Hessling 1
Affiliation  

To stop the coronavirus spread, new inactivation approaches are being sought that can also be applied in the presence of humans or even on humans. Here, we investigate the effect of visible violet light with a wavelength of 405 nm on the coronavirus surrogate phi6 in two aqueous solutions that are free of photosensitizers. A dose of 1300 J cm−2 of 405 nm irradiation reduces the phi6 plaque‐forming unit concentration by three log‐levels. The next step should be similar visible light photoinactivation investigations on coronaviruses, which cannot be performed in our lab.

中文翻译:

可见光对冠状病毒替代物 phi6 的光灭活

为了阻止冠状病毒的传播,正在寻找新的灭活方法,这些方法也可以应用于人类甚至人类。在这里,我们研究了波长为 405 nm 的可见紫光在两种不含光敏剂的水溶液中对冠状病毒替代物 phi6 的影响。1300 J cm-2 的 405 nm 辐射剂量将 phi6 斑块形成​​单位浓度降低三个对数水平。下一步应该是对冠状病毒进行类似的可见光光灭活研究,这在我们的实验室中是无法进行的。
更新日期:2020-11-21
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