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STEM CELLS ( IF 5.2 ) Pub Date : 2020-10-30 , DOI: 10.1002/stem.3293


Lung organoid at day 5, the earliest stage to exhibit expression of alveolar epithelial cell marker SFTPC (white) in organoids. Wnt activity is depicted by GFP (green) and proliferation by Ki67 (red) showing non‐overlapping staining. These results support the notion that cell proliferation following initial onset of alveolar organoid formation does not require Wnt/β‐catenin activation. See Hu et al. beginning on page 1467.
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中文翻译:

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在第5天,最早出现肺泡上皮细胞标记物SFTPC(白色)的肺类器官在类器官中表达。Wnt活性用GFP(绿色)表示,而Ki67(红色)则表示不重叠染色。这些结果支持了这样的观点,即在开始形成肺泡类器官后,细胞增殖不需要Wnt /β-catenin激活。参见Hu等。从第1467页开始。
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更新日期:2020-11-02
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