Selenium (Se) toxicity to fish is primarily manifested via maternal transfer to the eggs, which may result in adverse effects on larval survival and development. The present study assessed the effects of egg Se concentrations derived via maternal transfer on early life–stage development, survival, and growth of Arctic grayling (Thymallus arcticus), a salmonid species not previously assessed for Se sensitivity. Fish gametes were collected from 4 streams in Alaska known to exhibit a range of egg Se concentrations. Eggs were fertilized and reared in the laboratory from hatch through post‐swim‐up. Larvae were assessed for survival, length, and weight, as well as deformities (skeletal, craniofacial, fin‐fold) and edema based on a graduated severity index. Eggs from a total of 47 females were collected, with egg Se concentrations ranging from 3.3 to 33.9 mg kg⁻¹ dry weight. No relationships were observed between larval endpoints evaluated and parent females' egg, muscle, or whole‐body Se concentrations. Therefore, Se 10% effective concentrations (EC10s) were defined as the maximum measured Se concentrations: >33.9, >17.6, and >19.7 mg kg⁻¹ dry weight for eggs, muscle, and whole‐body tissue, respectively. Collectively, these data indicate that Arctic grayling are relatively insensitive to maternally transferred Se compared to other fish species. Environ Toxicol Chem 2021;40:380–389. © 2020 SETAC

中文翻译：

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母体转移的卵硒对北极鳟（Thymallus arcticus）胚胎-幼虫存活、生长和发育的影响

硒 (Se) 对鱼类的毒性主要通过母体转移到卵中表现出来，这可能会对幼虫的存活和发育产生不利影响。本研究评估了通过母体转移获得的卵硒浓度对北极鳟（Thymallus arcticus ）生命早期发育、存活和生长的影响)，一种以前未评估硒敏感性的鲑鱼物种。从阿拉斯加的 4 条溪流中收集了鱼配子，这些溪流显示出一系列鸡蛋硒浓度。卵从孵化到游泳后都在实验室受精和饲养。根据分级的严重程度指数评估幼虫的存活率、长度和体重，以及畸形（骨骼、颅面、鳍褶）和水肿。收集了总共 47 只雌性的鸡蛋，鸡蛋的硒浓度范围为 3.3 至 33.9 mg kg ^-1 干重。在评估的幼虫终点与亲本雌性的卵、肌肉或全身硒浓度之间没有观察到任何关系。因此，Se 10% 有效浓度 (EC10s) 被定义为最大测量 Se 浓度：>33.9、>17.6 和 >19.7 mg kg ^-1 分别为鸡蛋、肌肉和全身组织的干重。总的来说，这些数据表明，与其他鱼类相比，北极鲑鱼对母系转移的硒相对不敏感。环境毒理学化学2021；40：380-389。© 2020 SETAC