In the primate visual system, form (shape, location) and color information are processed in separate but interacting pathways. Recent access to high-resolution neuroimaging has facilitated the exploration of the structure of these pathways at the mesoscopic level in the human visual cortex. We used 7T fMRI to observe selective activation of the primary visual cortex to chromatic versus achromatic stimuli in five participants across two scanning sessions. Achromatic checkerboards with low spatial frequency and high temporal frequency targeted the color-insensitive magnocellular pathway. Chromatic checkerboards with higher spatial frequency and low temporal frequency targeted the color-selective parvocellular pathway. This work resulted in three main findings. First, responses driven by chromatic stimuli had a laminar profile biased towards superficial layers of V1, as compared to responses driven by achromatic stimuli. Second, we found stronger preference for chromatic stimuli in parafoveal V1 compared with peripheral V1. Finally, we found alternating, stimulus-selective bands stemming from the V1 border into V2 and V3. Similar alternating patterns have been previously found in both NHP and human extrastriate cortex. Together, our findings confirm the utility of fMRI for revealing details of mesoscopic neural architecture in human cortex.

中文翻译：

---

深度依赖的功能性 MRI 对整个 V1 和 V2 的彩色和无彩色刺激的反应

在灵长类视觉系统中，形式（形状、位置）和颜色信息在独立但相互作用的路径中进行处理。最近对高分辨率神经成像的使用促进了对人类视觉皮层中介观水平的这些通路结构的探索。我们使用 7T fMRI 观察了五名参与者在两次扫描过程中初级视觉皮层对彩色刺激和消色差刺激的选择性激活。具有低空间频率和高时间频率的消色差棋盘针对颜色不敏感的大细胞通路。具有较高空间频率和较低时间频率的彩色棋盘格针对颜色选择性细小细胞通路。这项工作产生了三个主要发现。第一的，与消色差刺激驱动的响应相比，色度刺激驱动的响应具有偏向 V1 表层的层流分布。其次，与周边 V1 相比，我们发现旁中央凹 V1 中对色度刺激的偏好更强。最后，我们发现从 V1 边界到 V2 和 V3 的交替刺激选择性带。之前在 NHP 和人类纹外皮层中都发现了类似的交替模式。总之，我们的研究结果证实了 fMRI 在揭示人类皮层中观神经结构细节方面的效用。之前在 NHP 和人类纹外皮层中都发现了类似的交替模式。总之，我们的研究结果证实了 fMRI 在揭示人类皮层中观神经结构细节方面的效用。之前在 NHP 和人类纹外皮层中都发现了类似的交替模式。总之，我们的研究结果证实了 fMRI 在揭示人类皮层中观神经结构细节方面的效用。