In Ayurveda, the age-old Indian traditional system of medicine, health is considered to be achieved as equilibrium of physical and mental wellbeing and brain related ailments are recognized as ‘Vatavyadi’. Rasayana herbs were mainly used for pharmacological treatment of neurological diseases and Tinospora cordifolia is one of the popular Rasayana herbs of Ayurveda. The traditional claims of therapeutic activity of this herb for treatment of fever, diabetes, anxiety, immunodeficiency, memory deficit and psychological problems have been explored by different research groups using reverse pharmacology and advance technological approaches. The aim of current review is to compile and discuss the neurotherapeutic potential of T. cordifolia in the light of various preclinical and clinical studies from literature. This review summarizes the information about different extracts of this herb and decoctions used for various neuro-related problems such as neurodegenerative diseases, neuroinflammation, sleep disorders, neural cancers, memory and cognition deficits and psychological problems besides other potential activities. The review also provides the knowledge of underlying therapeutic mechanism of T. cordifolia and its active phytoconstituents.

在古老的印度传统医学体系阿育吠陀中，健康被认为是通过身心健康的平衡来实现的，而与大脑相关的疾病被认为是“Vatavyadi”。Rasayana草药主要用于神经系统疾病的药物治疗，Tinospora cordifolia是阿育吠陀流行的Rasayana草药之一。不同的研究小组使用反向药理学和先进的技术方法探索了这种草药治疗发烧、糖尿病、焦虑、免疫缺陷、记忆力缺陷和心理问题的传统疗效。目前审查的目的是整理和讨论的neurotherapeutic潜力T.茜草根据文献中的各种临床前和临床研究。这篇综述总结了这种草药和汤剂的不同提取物的信息，用于治疗各种神经相关问题，如神经退行性疾病、神经炎症、睡眠障碍、神经癌症、记忆和认知缺陷以及除其他潜在活动之外的心理问题。该评论还提供了关于心叶木耳及其活性植物成分的潜在治疗机制的知识。